I load of 90 different cartridges. I HAVE consolidated.
That's a bigger problem! I don't have 90 guns! I don't even load for all of my collection.
I load 9mm, .40S&W, 10mm (same as 40 dies), .45ACP, .223 REM, .300BLK, .308 Win. I use W231 for all the pistol, and mostly Varget for the rifle, with some 1680 and 2015 when I run out of Varget.
I do NOT load for .38Spl/.357 Mag, .380
[spit], 30.06, 7.62x39 or 7.62x54R. I could probably load most of those with the powders I keep on hand, but buying dies, toolheads, conversion kits, etc for those would not be worth it.