been a few years since I've done any reloading, but when I was doing the Hunter Pistol silhouette, using a Ruger Blackhawk in .357, my best load was 165 gr, LSWC, over 6.2 grs of Unique. Interesting thing I found with this load was I could hold center at 25m, 50m and 75m and hold at the top of the back on the rams at 100m and never have to adjust my sights.
I used a slightly lighter load for indoor combat, Ruger Security six, 6 in, barrel, I don't really remember that load, but it was in the neighborhood of 5 grs of unique.
(very low budget operation at that time, about 30 years ago now. I could load up a back pack, strap it on the back of my Honda 400 Shadow and spend the afternoon at a shoot, pretty cheap fun when I was single )