I too, like the 158sfor all my .38Spl loads. I like the 158s for .357Mag (both jacketed and hard cast/gas ckecked) for anything1,250 and under, but I'd say my favorite weight for full power Magnum loads are the 140grs by the various makers. I think they have the right balance of weight and velocity...man will they knock the hell out of a coyote from both 6.5" Blackhawk and Marlin carbine!
Here's some other small rifle and shotshell powders I have had good, safe performance in magnum pistol ctgs, in addition to H4227 and IMR4227: Blue Dot, HS-6 & HS-7, H110, Win 571 and Vihtavuori's N350 & N110.
For the .38Spl: Blue Dot, Hi- SKOR 700-X, SR7625/4756, Red Dot, Universal Clays, WSL, Win 571 and Vihta's N320, N340.
I've used all the above with very to great results, but to be frank, my favorite all around powder for the handgun calibers I've loaded for is Blue Dot, originally a shotshell powder, it's excellent in 9mmx19, .38Spl and .357Mag, which I've loaded extensively. I've also loaded a bit of .38 Super w/ it and attained excellent results. When I was reloading, Blue Dot became my "go to" powder for all my handgun loads.
I might add that my son also has excellent results w/ Blue Dot in .38Spl, .45ACP and .45 Colt.